Research Initiatives
Where Purpose Meets Progress — accelerating LMS research through collaboration between scientists and patient communities.
Introduction
“Where Purpose Meets Progress – accelerating progress for Leiomyosarcoma research, through advancing collaborative priorities of the research community and the patient communities served by the NLMSF.”
Dedication: This website is dedicated to Gilles Frydman and to all the contributors of the original Leiomyosarcoma.info website (listed here) who provided a valuable compass to guide LMS patients, caregivers, and families.
This research site is also dedicated to the heroes among us — patients and families — and the researchers who work tirelessly to better understand this rare and complex sarcoma, advancing treatment options and improving survivorship.
International LMS Research Roundtable
A global initiative bringing together the Sarcoma Research Community for a collaborative focus on the future of Leiomyosarcoma investigational research and clinical trials with a mission of:
- Bringing together sarcoma experts for a focused meeting only on Leiomyosarcoma.
- Discussing and understanding the current state of LMS with its research, diagnosis, and treatment challenges.
- Developing work plans to close gaps and improve precision LMS research and patient-treatment protocols — SEE PUBLICATION: Publication
- Advising and directing the NLMSF on LMS precision research projects, including solicitation and funding of grant proposals.
Current Roundtable Workgroups
- LMS Cell Lines / PDX Models
- Multiomics
- Gynecologic / STUMP
- Clinical Trials Assessment
- Imaging Strategies and Radiomics
Leiomyosarcoma Information
Unmet Needs & Future Perspectives
NLMSF & SPAEN Position Paper
Unmet Medical Needs and Future Perspectives for Leiomyosarcoma Patients — a position paper from the National Leiomyosarcoma Foundation (NLMSF) and Sarcoma Patients EuroNet (SPAEN).
Principal Author: Bernd Kasper, MD, PhD
Professor, Universitätsmedizin Mannheim | NLMSF–SPAEN Executive Committee | International LMS Research Roundtable
What Clinical Trials are Needed for LMS?
Comprehensive Research Publications
Lineage-defined leiomyosarcoma subtypes emerge years before diagnosis and determine patient survival
General Sarcoma Information
Voices from the Research Community
Scott Okuno, MD — Professor of Oncology, Mayo Clinic
“We are continuously updating this website to provide information on advances in Leiomyosarcoma research as well as the numerous collaborations that are occurring. The NLMSF has additional resources about Leiomyosarcoma on the NLMSF.org site. We are interested in your feedback as we continue to strive to improve sharing of Leiomyosarcoma information.”
Seth Pollack, MD — Director, Sarcoma Program, Lurie Cancer Center
“I love the NLMSF – I love the patient programs held – your signature support advocacy to collaborate with sarcoma centers. LMS is common enough to have had a specific focus initiative — and the NLMSF was many steps ahead of the curve to launch the LMS International Research Roundtable — to support patients in this way, and focus on LMS-specific research and support in the research landscape.”
Arun Singh, MD — Associate Professor, Sarcoma Service, UCLA
“The National Leiomyosarcoma Foundation is an important organization that strives to gather a critical mass of patients, scientists, patient advocates and physicians to learn more about this rare disease. Within the NLMSF, the LMS Research Roundtable organizes cutting-edge research and strives to innovate the ways that this disease is treated.”
Funding & Collaborative News
University of Michigan to lead multi-site $12M grant to study rare sarcoma
“We recognized that to effectively study a rare cancer we had to assemble an outstanding international team from premier sarcoma centers,” said principal investigator Scott Schuetze, MD, PhD.
The NLMSF is proud to have committed to a five-year funding pledge of support for this LMS-specific research, and pleased that Dr. Mitch Achee (LMS survivor and physician) was selected to be a member of the External Advisory Board for the SPORE. He will lead the engagement of the LMS patient advocate group for this initiative.
— Annie Achee, NLMSF
NLMSF Collaborators
Charity & GuideStar Seals
