These videos provide information about clinical trials for Leiomyosarcoma, including how to find appropriate trials, what to expect, and how to determine if a trial is right for you.
YouTube Recording
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Maggie Zhou, MD
Medical Oncologist, Stanford University, Stanford, CA
Leiomyosarcoma Specific Research, Clinical Trials & Forthcoming ctDNA Research Project
Dr. Zhou presents on Leiomyosarcoma-specific research and clinical trials, including a forthcoming ctDNA research project aimed at advancing detection and treatment monitoring for LMS patients.
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Dr. Candace Haddox
Dana-Farber Cancer Institute and Harvard Medical School, Boston, MA
Phase 1 Clinical Trial Using Peposertib and Liposomal Doxorubicin
February 26, 2025
Dr. Haddox discusses a novel Phase 1 clinical trial using Peposertib (M3814) and low-dose Liposomal Doxorubicin for metastatic Leiomyosarcoma and other soft tissue sarcomas.
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Dr. Seth Pollack
Lurie Cancer Center, Northwestern University, Chicago, IL
Phase II Clinical Trial Using Zanzalintinib (XL092)
January 31, 2025
Dr. Pollack discusses a Phase II clinical trial for Leiomyosarcoma patients using Zanzalintinib, a Tyrosine Kinase Inhibitor, currently enrolling at Northwestern University.
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Dr. John Mullinax
Moffitt Cancer Center, Tampa, FL
STRASS 2/3 Clinical Trial for Retroperitoneal Leiomyosarcoma
January 2025
Dr. Mullinax discusses the STRASS 2/3 clinical trial for the initial treatment of retroperitoneal Leiomyosarcoma and Liposarcoma.
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Dr. Vishu Avutu
Memorial Sloan Kettering Cancer Center, New York, NY
Phase 1a/2 Clinical Trial of GI-102 for Advanced Sarcoma
August 2024
Dr. Avutu discusses a Phase 1a/2 clinical trial of GI-102, which boosts the immune system by blocking CTLA-4 and increasing immune cells via IL-2, for advanced sarcoma patients.
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Expert Panel
Multiple Institutions
Clinical Trials Perspectives
February 2024
A panel discussion by sarcoma medical oncologists on clinical trials for Leiomyosarcoma and other sarcomas.
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Dr. Gregory Cote
Massachusetts General Hospital, Boston, MA
Lurbinectedin in Combination with Doxorubicin for Advanced Leiomyosarcoma
August 8, 2023
Dr. Cote provides an overview of clinical trials and discusses his trial using Lurbinectedin with Doxorubicin for advanced Leiomyosarcoma.
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Dr. Brian Van Tine
Siteman Cancer Center, Washington University, St. Louis, MO
Cabozantinib with PD-1 and CTLA-4 Inhibition and Other Trials
July 20, 2023
Dr. Van Tine discusses a Phase II trial of Cabozantinib with PD-1 and CTLA-4 inhibition and updates on three ongoing trials: Unesbulin, Pegylated Arginine Deiminase, and Olaparib with Temozolomide.
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Dr. Brian Van Tine
Siteman Cancer Center, Washington University, St. Louis, MO
Updates on Three Promising Active LMS Clinical Trials
April 14, 2023
Dr. Van Tine provides updates on three promising clinical trials for Leiomyosarcoma patients.
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Dr. Elise Nassif
MD Anderson Cancer Center, Houston, TX
The Efficacy of Early-Phase Clinical Trials in Soft Tissue Sarcoma
September 21, 2022
Dr. Nassif discusses the efficacy of early-phase clinical trials in soft tissue sarcomas, including Leiomyosarcoma.
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Dr. Brian Van Tine
Siteman Cancer Center, Washington University, St. Louis, MO
Unesbulin, New Treatment for Leiomyosarcoma
June 28, 2022
Dr. Van Tine discusses Unesbulin (PTC596) as a new treatment for Leiomyosarcoma in an upcoming clinical trial.
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Dr. Matthew Ingham
Herbert Irving Comprehensive Cancer Center, Columbia University Medical Center, New York, NY
New Treatment Approaches for LMS in Preclinical or Clinical Trials
June 8, 2022
Dr. Ingham discusses new treatment approaches for Leiomyosarcoma in preclinical and clinical trials, including ATX-101 and Olaparib with Temozolomide.
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Dr. Gary Schwartz
Herbert Irving Comprehensive Cancer Center, Columbia University Medical Center, New York, NY
Olaparib and Temozolomide for Advanced Uterine Leiomyosarcoma
August 24, 2022
Dr. Schwartz discusses a Phase II clinical trial evaluating Olaparib and Temozolomide for advanced uterine Leiomyosarcoma, moving to Phase III.
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Varun Monga, MD
Sarcoma Medical Oncologist — UCSF, San Francisco, CA
Clinical Trials Discussion
Hosted by the NLMSF. Dr. Monga discusses clinical trials relevant to Leiomyosarcoma patients.
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